COVID-19 and Black Fungus: What Is Mucormycosis?
Many people recovering from COVID-19 have recently had black fungal disease or mucormycosis. The fungus enters the sinuses and reaches the intraorbital and intracranial regions. If the progression is not controlled early, 50 to 80% of patients may die.
Both authors are plant biologists interested in fungi. When we first heard about mucormycosis last year, according to reports in Europe, the doorbell rang.
People most often have mushrooms in their kitchen when fruit is rotting or bread is moldy. Fungi evolved 400 million years ago and play an important role on earth. They helped plants move to land from their aquatic habitats and helped them extract minerals from the soil. Fungi break down organic waste and recycle nutrients trapped in leaves and wood.
Some of them have also evolved into plant pathogens: they infect plants, reproduce and disperse in other plants, leaving destruction behind. The Great Irish Famine of 1845, which killed a million people, was the work of the fungus Phytophthora infestans, which wiped out the country’s staple potato crop.
While fungal diseases are common in plants, only a very small proportion of them affect humans. One of the reasons is that animals, including humans, have developed complex immune systems.
However, when the immune system has been damaged by another disease, the otherwise harmless fungi take advantage and invade human tissue. These are called opportunistic infections. Even so, unlike their pathogenic bacterial counterparts, fungi rarely cause fatal disease. Certain fungi, such as candida yeast, can sometimes cause serious infections. Candida lives on the skin and in the mouth, throat and vagina of healthy individuals without causing problems. However, if the host’s body has been weakened by some other disease or medication, it can lead to oral thrush, diaper rash, and vaginal infections.
Black Fungal Infection
Fungal Infection Overview
Mucormycosis is also know as Black Fungal Infection Treatment cost In Hyderabad a serious but rare fungal infection caused by a group of molds called mucormycetes. These molds live throughout the environment. Mucormycosis mainly affects people who have health problems or take medicines that lower the body’s ability to fight germs and sickness. It most commonly affects the sinuses or the lungs after inhaling fungal spores from the air. It can also occur on the skin after a cut, burn, or other type of skin injury.
What Causes Mucormycosis?
- Mucormycosis, also known as black fungus or zygomycosis, is caused by a group of mould called mucormycetes.
- These fungi live in the environment, particularly in soil and in decaying organic matter, such as leaves, compost piles, or rotten wood, according to the Center for Disease Control and Prevention.
Symptoms of Mucormycosis
Symptoms of rhinocerebral (sinus and brain) mucormycosis include:
- One-sided facial swelling
- Headache
- Nasal or sinus congestion
- Black lesions on nasal bridge or upper inside of mouth that quickly become more severe
- Fever
Symptoms of pulmonary (lung) mucormycosis include:
- Fever
- Cough
- Chest pain
- Shortness of breath
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People at Risk & Prevention Black Fungal Infection Treatment cost In Hyderabad
Who gets mucormycosis?
Mucormycosis is rare, but it’s more common among people who have health problems or take medicines that lower the body’s ability to fight germs and sickness. Certain groups of people are more likely to get mucormycosis, 1–3 including people with:
- Diabetes, especially with diabetic ketoacidosis
- Cancer
- Organ transplant
- Stem cell transplant
- Neutropenia pdf icon[PDF – 2 pages] (low number of white blood cells)
- Long-term corticosteroid use
- Injection drug use
- Too much iron in the body (iron overload or hemochromatosis)
- Skin injury due to surgery, burns, or wounds
- Prematurity and low birthweight (for neonatal gastrointestinal mucormycosis)
Is mucormycosis contagious?
No. Mucormycosis can’t spread between people or between people and animals.
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13 Exact Information about Black Fungal Infection Treatment cost In Hyderabad?
Where Mucormycosis Comes From
How is mucormycosis diagnosed?
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Treatment for Mucormycosis
How is mucormycosis treated?
IV bag for antifungal medicine, usually amphotericin B, posaconazole, or isavuconazole
Mucormycosis is a serious infection and needs to be treated with prescription antifungal medicine, usually amphotericin B, posaconazole, or isavuconazole. These medicines are given through a vein (amphotericin B, posaconazole, isavuconazole) or by mouth (posaconazole, isavuconazole). Other medicines, including fluconazole, voriconazole, and echinocandins, do not work against fungi that cause mucormycosis. Often, mucormycosis requires surgery to cut away the infected tissue
Types of mucormycosis
- Rhinocerebral (sinus and brain) mucormycosis is an infection in the sinuses that can spread to the brain. This form of mucormycosis is most common in people with uncontrolled diabetes and in people who have had a kidney transplant. 7-8
- Pulmonary (lung) mucormycosis is the most common type of mucormycosis in people with cancer and in people who have had an organ transplant or a stem cell transplant.
- Gastrointestinal mucormycosis is more common among young children than adults, especially premature and low birth weight infants less than 1 month of age, who have had antibiotics, surgery, or medications that lower the body’s ability to fight germs and sickness. 9-10
- Cutaneous (skin) mucormycosis: occurs after the fungi enter the body through a break in the skin (for example, after surgery, a burn, or other type of skin trauma). This is the most common form of mucormycosis among people who do not have weakened immune systems.
- Disseminated mucormycosis occurs when the infection spreads through the bloodstream to affect another part of the body. The infection most commonly affects the brain, but also can affect other organs such as the spleen, heart, and skin.
How can fungal infections be prevented?
Good hygiene is also critical for avoiding fungal infections.
Try to:
keep your skin clean and dry, particularly the folds of your skin
wash your hands often, especially after touching animals or other people
avoid using other people’s towels and other personal care products
wear shoes in locker rooms, community showers, and swimming pools
wipe gym equipment before and after using it
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